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PD-1 Non-Small Cell Lung Cancer (PD-1+ NSCLC) Pipeline and Clinical Trials Assessment 2023: FDA Approvals, Therapies and Key Companies involved by DelveInsight | Pfizer, AstraZeneca, Lepu Biopharma

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PD-1 Non-Small Cell Lung Cancer (PD-1+ NSCLC) Pipeline and Clinical Trials Assessment 2023: FDA Approvals, Therapies and Key Companies involved by DelveInsight | Pfizer, AstraZeneca, Lepu Biopharma

September 05
00:45 2023
PD-1 Non-Small Cell Lung Cancer (PD-1+ NSCLC) Pipeline and Clinical Trials Assessment 2023: FDA Approvals, Therapies and Key Companies involved by DelveInsight | Pfizer, AstraZeneca, Lepu Biopharma
(Las Vegas, Nevada, United States) As per DelveInsight’s assessment, globally, PD-1 Non-Small Cell Lung Cancer pipeline constitutes 30+ key companies continuously working towards developing 30+ PD-1 Non-Small Cell Lung Cancer treatment therapies, analysis of Clinical Trials, Therapies, Mechanism of Action, Route of Administration, and Developments analyzes DelveInsight.

The PD-1 Non-Small Cell Lung Cancer Pipeline report embraces in-depth commercial and clinical assessment of the pipeline products from the pre-clinical developmental phase to the marketed phase. The report also covers a detailed description of the drug, including the mechanism of action of the drug, clinical studies, NDA approvals (if any), and product development activities comprising the technology, collaborations, mergers acquisition, funding, designations, and other product-related details.

 

PD-1 Non-Small Cell Lung Cancer Pipeline Insight, 2023 report by DelveInsight outlines comprehensive insights into the present clinical development scenario and growth prospects across the PD-1 Non-Small Cell Lung Cancer Market.

 

Some of the key takeaways from the PD-1 Non-Small Cell Lung Cancer Pipeline Report:

  • Companies across the globe are diligently working toward developing novel PD-1 Non-Small Cell Lung Cancer treatment therapies with a considerable amount of success over the years. 
  • PD-1 Non-Small Cell Lung Cancer companies working in the treatment market are Genor Biopharma, Shandong Boan Biotechnology, Pfizer, AstraZeneca, Lepu Biopharma, GlaxoSmithKline, Incyte Corporation, Akeso Biopharma, Arcus Biosciences, Summit Therapeutics, Pfizer, AstraZeneca, Seagen, and others, are developing therapies for the PD-1 Non-Small Cell Lung Cancer treatment 
  • Emerging PD-1 Non-Small Cell Lung Cancer therapies in the different phases of clinical trials are- GB226, BA-1104, PF-06801591, AZD2936, HX008, Dostarlimab, INCMGA00012, AK-112, Zimberelimab, Ivonescimab, Sasanlimab, Rilvegostomig, SGN-PDL1V, and others are expected to have a significant impact on the PD-1 Non-Small Cell Lung Cancer market in the coming years.   
  • In February 2021, Arcus Biosciences initiated a Randomized Phase III Open-label Study will Evaluate the Efficacy of Zimberelimab (AB122) Monotherapy Compared to Standard Chemotherapy or Zimberelimab Combined with AB154 in Front-Line, PD-L1-Positive Locally Advanced or Metastatic Non-Small Cell Lung Cancer.
  • In June 2023, At the 2023 American Society of Clinical Oncology Annual Meeting (ASCO 2023), Qilu Pharmaceutical presented trials in progress posters on QL1706 (iparomlimab/tuvonralimab), a novel bifunctional antibody for immunotherapy, in two Phase III non-small cell lung carcinoma (NSCLC) clinical studies.
  • In May 2023, The Phase III HARMONi study’s first patient from the United States has been enrolled, according to a statement from Summit Therapeutics. Phase III multiregional, randomised, double-blinded study called HARMONi. Patients with locally advanced or metastatic non-squamous non-small cell lung cancer (NSCLC) with an epidermal growth factor receptor (EGFR) mutation who have progressed following treatment with a third-generation EGFR tyrosine kinase inhibitor (TKI), such as osimertinib, will be included in the study to assess the efficacy and safety of ivonescimab combined with chemotherapy.
  • In May 2023, Updated findings from an interim analysis of the ARC-7 study in patients with first-line, metastatic non-small cell lung cancer (NSCLC) and PD-L1 tumour proportion score (TPS) of 50% without EGFR or anaplastic lymphoma kinase (ALK) mutations were released by Gilead Sciences and Arcus Biosciences. The early separation of both domvanalimab-containing arms from the zimberelimab arm, which was consistently maintained, was evident from the progression-free survival curves, supporting the potential therapeutic effect of blocking the TIGIT pathway.
  • In October 2022,  Ivonescimab (PD-1/VEGF bispecific antibody, AK112) combined with docetaxel for the treatment of patients with locally advanced or metastatic non-small cell lung cancer (NSCLC) who did not respond to prior PD-(L)1 inhibitor combined with platinum-based doublet chemotherapy was awarded Breakthrough Therapy Designation (BTD), according to a statement from Akeso Biopharma.
  • In October 2022, GSK released encouraging preliminary findings from PERLA, a phase II trial of chemotherapy and Jemperli (dostarlimab) in patients with metastatic non-squamous non-small cell lung cancer. Dostarlimab’s safety and tolerability profile in the PERLA phase II trial was in line with that of earlier clinical studies using comparable regimens. Anaemia, asthenia, nausea, constipation, cough, dyspnea, vomiting, decreased appetite, and neutropenia were the adverse events that most frequently appeared as a result of treatment.

 

PD-1 Non-Small Cell Lung Cancer Overview

The poor prognosis of lung cancer means that it continues to be the primary cause of cancer-related mortality worldwide. Positively, immune checkpoint inhibition targeting PD-1 and PD-L1 has significantly altered the landscape of available treatments for people with non-small-cell lung cancer (NSCLC).

 

Get a Free Sample PDF Report to know more about PD-1 Non-Small Cell Lung Cancer Pipeline Therapeutic Assessment-

https://www.delveinsight.com/report-store/pd-1-non-small-cell-lung-cancer-pd-1-nsclc-pipeline-insight

 

Emerging PD-1 Non-Small Cell Lung Cancer Drugs Under Different Phases of Clinical Development Include:

  • GB226: Genor Biopharma
  • BA-1104: Shandong Boan Biotechnology
  • PF-06801591: Pfizer
  • AZD2936: AstraZeneca
  • HX008: Lepu Biopharma
  • Dostarlimab: GlaxoSmithKline
  • INCMGA00012: Incyte Corporation
  • AK-112: Akeso Biopharma
  • Zimberelimab: Arcus Biosciences
  • Ivonescimab: Summit Therapeutics
  • Sasanlimab: Pfizer
  • Rilvegostomig: AstraZeneca
  • SGN-PDL1V: Seagen

 

PD-1 Non-Small Cell Lung Cancer Route of Administration

PD-1 Non-Small Cell Lung Cancer pipeline report provides the therapeutic assessment of the pipeline drugs by the Route of Administration. Products have been categorized under various ROAs, such as 

  • Oral
  • Parenteral
  • Intravenous
  • Subcutaneous
  • Topical

 

PD-1 Non-Small Cell Lung Cancer Molecule Type

PD-1 Non-Small Cell Lung Cancer Products have been categorized under various Molecule types, such as

  • Monoclonal Antibody
  • Peptides
  • Polymer
  • Small molecule
  • Gene therapy 

 

PD-1 Non-Small Cell Lung Cancer Pipeline Therapeutics Assessment

  • PD-1 Non-Small Cell Lung Cancer Assessment by Product Type
  • PD-1 Non-Small Cell Lung Cancer By Stage and Product Type
  • PD-1 Non-Small Cell Lung Cancer Assessment by Route of Administration
  • PD-1 Non-Small Cell Lung Cancer By Stage and Route of Administration
  • PD-1 Non-Small Cell Lung Cancer Assessment by Molecule Type
  • PD-1 Non-Small Cell Lung Cancer by Stage and Molecule Type

 

DelveInsight’s PD-1 Non-Small Cell Lung Cancer Report covers around 30+ products under different phases of clinical development like

  • Late-stage products (Phase III)
  • Mid-stage products (Phase II)
  • Early-stage product (Phase I)
  • Pre-clinical and Discovery stage candidates
  • Discontinued & Inactive candidates
  • Route of Administration

 

Further PD-1 Non-Small Cell Lung Cancer product details are provided in the report. Download the PD-1 Non-Small Cell Lung Cancer pipeline report to learn more about the emerging PD-1 Non-Small Cell Lung Cancer therapies

 

Some of the key companies in the PD-1 Non-Small Cell Lung Cancer Therapeutics Market include:

Key companies developing therapies for PD-1 Non-Small Cell Lung Cancer are – Summit Therapeutics, Arcus Biosciences, GlaxoSmithKline, Pfizer, AstraZeneca, Seagen, MacroGenics, Roche, Qilu Pharmaceutical, Shandong New Age Pharmaceutical, Symphogen, and others.

 

PD-1 Non-Small Cell Lung Cancer Pipeline Analysis:

The PD-1 Non-Small Cell Lung Cancer pipeline report provides insights into 

  • The report provides detailed insights about companies that are developing therapies for the treatment of PD-1 Non-Small Cell Lung Cancer with aggregate therapies developed by each company for the same.
  • It accesses the Different therapeutic candidates segmented into early-stage, mid-stage, and late-stage of development for PD-1 Non-Small Cell Lung Cancer Treatment.
  • PD-1 Non-Small Cell Lung Cancer key companies are involved in targeted therapeutics development with respective active and inactive (dormant or discontinued) projects.
  • PD-1 Non-Small Cell Lung Cancer Drugs under development based on the stage of development, route of administration, target receptor, monotherapy or combination therapy, a different mechanism of action, and molecular type. 
  • Detailed analysis of collaborations (company-company collaborations and company-academia collaborations), licensing agreement and financing details for future advancement of the PD-1 Non-Small Cell Lung Cancer market.

The report is built using data and information traced from the researcher’s proprietary databases, company/university websites, clinical trial registries, conferences, SEC filings, investor presentations, and featured press releases from company/university websites and industry-specific third-party sources, etc.

 

Download Sample PDF Report to know more about PD-1 Non-Small Cell Lung Cancer drugs and therapies

 

PD-1 Non-Small Cell Lung Cancer Pipeline Market Drivers

  • Increase in Patient Burden, development of Efficient Novel Treatments, increasing healthcare expenditures are some of the important factors that are fueling the PD-1 Non-Small Cell Lung Cancer Market.

 

PD-1 Non-Small Cell Lung Cancer Pipeline Market Barriers

  • However, uncertainty about the clinical response to PD-1/PD-L1 blockade therapy in NSCLC, NSCLC with driver mutations represent a challenging population and other factors are creating obstacles in the PD-1 Non-Small Cell Lung Cancer Market growth.

 

Scope of PD-1 Non-Small Cell Lung Cancer Pipeline Drug Insight    

  • Coverage: Global
  • Key PD-1 Non-Small Cell Lung Cancer Companies: Genor Biopharma, Shandong Boan Biotechnology, Pfizer, AstraZeneca, Lepu Biopharma, GlaxoSmithKline, Incyte Corporation, Akeso Biopharma, Arcus Biosciences, Summit Therapeutics, Pfizer, AstraZeneca, Seagen, and others
  • Key PD-1 Non-Small Cell Lung Cancer Therapies: GB226, BA-1104, PF-06801591, AZD2936, HX008, Dostarlimab, INCMGA00012, AK-112, Zimberelimab, Ivonescimab, Sasanlimab, Rilvegostomig, SGN-PDL1V, and others
  • PD-1 Non-Small Cell Lung Cancer Therapeutic Assessment: PD-1 Non-Small Cell Lung Cancer current marketed and PD-1 Non-Small Cell Lung Cancer emerging therapies
  • PD-1 Non-Small Cell Lung Cancer Market Dynamics: PD-1 Non-Small Cell Lung Cancer market drivers and PD-1 Non-Small Cell Lung Cancer market barriers 

 

Request for Sample PDF Report for PD-1 Non-Small Cell Lung Cancer Pipeline Assessment and clinical trials

 

Table of Contents 

1. PD-1 Non-Small Cell Lung Cancer Report Introduction

2. PD-1 Non-Small Cell Lung Cancer Executive Summary

3. PD-1 Non-Small Cell Lung Cancer Overview

4. PD-1 Non-Small Cell Lung Cancer- Analytical Perspective In-depth Commercial Assessment

5. PD-1 Non-Small Cell Lung Cancer Pipeline Therapeutics

6. PD-1 Non-Small Cell Lung Cancer Late Stage Products (Phase II/III)

7. PD-1 Non-Small Cell Lung Cancer Mid Stage Products (Phase II)

8. PD-1 Non-Small Cell Lung Cancer Early Stage Products (Phase I)

9. PD-1 Non-Small Cell Lung Cancer Preclinical Stage Products

10. PD-1 Non-Small Cell Lung Cancer Therapeutics Assessment

11. PD-1 Non-Small Cell Lung Cancer Inactive Products

12. Company-University Collaborations (Licensing/Partnering) Analysis

13. PD-1 Non-Small Cell Lung Cancer Key Companies

14. PD-1 Non-Small Cell Lung Cancer Key Products

15. PD-1 Non-Small Cell Lung Cancer Unmet Needs

16 . PD-1 Non-Small Cell Lung Cancer Market Drivers and Barriers

17. PD-1 Non-Small Cell Lung Cancer Future Perspectives and Conclusion

18. PD-1 Non-Small Cell Lung Cancer Analyst Views

19. Appendix

20. About DelveInsight

 

About DelveInsight

 

DelveInsight is a leading Business Consultant and Market Research firm focused exclusively on life sciences. It supports Pharma companies by providing comprehensive end-to-end solutions to improve their performance. It also offers Healthcare Consulting Services, which benefits in market analysis to accelerate business growth and overcome challenges with a practical approach.

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